90% of lipids and their products of digestion enter the liver on hepatic arteria. 10% of products of lipids digestion enter the liver through portal vein. tHe following processes occur in liver:
I. Anabolic processes: 1) lipogenesis (formation of TAG and PhL) on Phosphatidic pathway; 2) synthesis of Cholesterol and its esters; 3) storage of esters of cholesterol; 4) synthesis of ketone bodies; 5) formation of lipoproteins (LP); 6) synthesis of FFA; 7) liponeogenesis
II. Catabolic processes: 1) lipolysis; 2) beta-oxidation of FFA; 3) oxidation of Glycerol; 4) oxidation of cholesterol to bile acids; 5) lipid peroxidation
The role of adipose tissue in Lipid Metabolism:
1) lipogenesis on Phosphatidic pathway
2) storage of TAG
3) lipolysis
4) liponeogenesis
5) the formation of leptin. Leptin causes the sense of saturation by food. Its synthesis is destroyed in primary obesity that results in invert food behavior
Lipids metabolism. lipoproteins, their composition and role. the pathways of usage of glycerol and free fatty acids in cells